On the contrary to chemotherapy, radiotherapy kills cancerous cells only in radiated region and thus, recurrence of the disease in radiated region is prevented or minimized. Chemotherapy refers to administration of anti-cancer drugs via intravenous line in order to deliver drug to whole body and thus, all tumor cells located in tissues are killed.
Radiation Oncology uses devices which enable three-dimensional conformal and dose-adjusted radiotherapy. Such devices are products of state-of-the-art technology and they ensure elimination of cancer cells and minimize the possibility of recurrence by enabling use of high therapy doses. They may be used for both superficial and deep tumors. Also, the device is characterized with whole- or partial-body radiation. Whole body radiation is required particularly in bone marrow transplantation and a type of skin lymphoma.
PET-CT is used as pathfinder when radiotherapy is planned for cancer patients in Radiation Oncology department and thus, the possibility to miss viable tumor cells is eliminated. When this method is used, even smallest tissue involving tumor cell is identified and tumor is completely targeted and involved in radiated area. This approach enhances control rate and increases survival rate.
PET-CT has a significant position in early diagnosis and treatment of cancer. PET-CT enables imaging whole body at metabolic and molecular level and it offers diagnostic skills for cancerous areas with millimetric size.
PET is a method where vascularization, metabolism and viability of tissues are shown in three dimensional images. PET-CT is a system combining PET and computerized tomography in single device.
PET-CT is most commonly used in oncologic diseases and it offers ease of use and highest level of comfort ranging from primary diagnosis of cancer, grading, determination of extent, treatment response to determine viable cancer load for planning therapy in all oncologic patients.
Principal fields of use of PET-CT:
- Early diagnosis and staging,
- Determining whether the therapy will be of benefit,
- Best effective therapy of cancerous region,
- Minimizing side effects originating from therapy,
- Monitoring recurred in treated area and thus, preventing patient from unnecessary chemotherapy administrations,
- In cardiologic patients, determining post-infarction viability of heart muscle,
- Determining eligibility of patients for by-pass or stent operation,
- Identifying priority of surgery in epileptic patients,
- Early diagnosis of Alzheimer’s disease.
Recently, Radiation Oncology offers three-dimensional conformal brachytherapy. Radiation sources and special applicators, which were previously placed into patient’s body, are imaged using computerized tomography device and they are transferred to planning system. Thus, accuracy of procedure is controlled and if any fault is determined, it is corrected before therapy is applied. Patient is provided therapy after three-dimensional image is obtained and necessary calculations are made. This system also eliminates the risk of missing tumor.