Graduate Education

Uludağ University Cerrahpaşa School of Medicine(2000)

Postgraduate Education

(Residency) Uludağ University School of Medicine, InternalMedicine and Medical Oncology Residency Program (2005)

Area of Expertise

Medical Oncology

Internal Medicine

Experience

Uludağ University School of Medicine, Internal

Medicine and Medical Oncology Residency Program

Bursa AOS Oncology Hospital

Medical Park Hospital, Bursa

Istanbul Italian Oncology Hospital

Ortadoğu Hospital

Ruhr Hospital hyperthermia and Integrative oncology education

Medicana International Hospital, Istanbul, Medical Oncology Department

Publications
A. Articles published in international refereed journals
A1. A cross-sectional survey of the diagnosis and management of bone metastasis in breastcancer patients in Turkey. Arican A1, Bozkurt T, Bozcuk H, Demirkan B, Buyukberber S, Alkis N, Sanli UA, Camci C, Yildiz M, Yucel I, Uygun K, Aslay I, Demiray M, BeseNS, Isikdogan A, Bahat Z, Gemici C, Ozdemir F, Ozdener F, Pekin B. Support Care Cancer. 2014 Apr 22.
A2. Demiray M, Kurt E, Evrensel T, Kanat O, Arslan M, Saraydaroglu O, Ercan I, Gonullu G, Gokgoz S, Topal U, Tolunay S, Tasdelen I, Manavoglu O. Phase II Study Of Gemcitabine Plus Paclitaxel In Metastatic Breast Cancer Patients With Prior Anthracycline Exposure. Cancer Investigation 2005;23(5):386-91.

A3. Demiray M, Gulten M, Manavoglu O, Evrensel T, Ulukaya E, Yerci O, Kanat O, Kurt E, Arslan M, Gonullu G, Demiray H, Gulten T, Memik F. Evaluation of the effects of Helicobacter pylori eradication therapy on gastric antral epithelial hyperproliferation: a prospective six-month follow-up study.Hepatogastroenterology. 2004 Sep-oct;51(59): 1531-5.

A4. Demiray M, Ulukaya E , Arslan M, Gokgoz S, Saraydaroglu O, Ercan I, Evrensel T, Manavoglu O. Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin
18: A Prospective Pilot Study,” has been accepted for publication in Cancer Investigation. It is currently scheduled for publication in Vol. 24, issue 8.
A5. Gulten T, Tokyay N, Demiray M, Gulten M, Ercan I, Evke E, Sardas S, Karakaya
AE. The role of triple therapy, age, gender and smoking on the genotoxic effects of Helicobacter pylori infection. J Int Med Res. 2002 Jul-Aug;30(4):380-5.
A6. Arslan M, Evrensel T, Kurt E, Demiray M, Ercan I, Kanat O, Ozkan A, Manavoglu O. Comparison of the serum erythropoietin levels in chemotherapy-naive and cisplatin-treated
cancer patients. Neoplasma. 2005;52(1):43-5.
A7. Arslan M, Evrensel T, Kurt E, Demiray M, Gonullu G, Kanat O, Manavoglu O. Comparison of clinical outcomes of different erythropoietin usage strategies. Tumori. 2004 Jul-Aug;90(4):394-8.
A8. Kanat O, Evrensel T, Kurt E, Demiray M, Gonullu G, Arslan M, Manavoglu O. Treatment of metastatic pancreatic cancer with a combination of gemcitabine and 5- fluorouracil: a single center phase II study. Tumori. 2004 Mar-Apr;90(2):192-5.
A9. Kanat O, Evrensel T, Manavoglu O, Demiray M, Kurt E, Gonullu G, Kiyici M, Arslan M. Single-agent irinotecan as second-line treatment for advanced gastric cancer. Tumori. 2003 Jul-Aug;89(4):405-7.
A10. Kanat O, Adim S, Evrensel T, Yerci O, Ediz B, Kurt E, Demiray M, Gonullu G, Arslan M, Manavoglu O.Prognostic value of nm23 in gastrointestinal stromal tumors. Med Oncol.
2004; 21(1):53-8.
A11. Kurt E, Sezgin C, Evrensel T, Yalcinkaya U, Kanat O, Veral A, Demiray M, Arslan M, Karabulut M, Ercan I, Goker E, Manavoglu O. Therapy, outcome and analysis of c-kit
expression in patients with extrapulmonary carcinoma Int J Clin Pract. 2005 May;59(5):537-43.
A12. Kanat O, Evrensel T, Baran I, Coskun H, Zarifoglu M, Turan OF, Kurt E, Demiray M, Gonullu G, Manavoglu O. Protective effect of amifostine against toxicity of paclitaxel and carboplatin in non-small cell lung cancer: a single center randomized study. Med Oncol. 2003;20(3):237-45.
A13. Kanat O, Evrensel T, Adim SB, Yavascaoglu I, Kurt E, Demiray M, Gonullu G, Manavoglu O. Small cell carcinoma of the urinary bladder. A clinicopathologic study of five
cases. Tumori. 2003 May-Jun;89(3):328-30.
A14. Alper E, Gurel M, Evrensel T, Ozkocaman V, Akbunar T, Demiray M.99mTc-MIBI scintigraphy in untreated stage III multiple myeloma: comparison with X-ray skeletal survey and bone scintigraphy. Nucl Med Commun. 2003 May;24(5):537-42.
A15. Kanat O, Evrensel T, Demiray M, Kurt E, Gonullu G, Arslan M, Manavoglu O, Ozkan  A. Cisplatin plus etoposide in advanced non-small cell lung cancer patients age of 70 years or
older. Lung Cancer. 2003 Aug;41(2):233-4.
A16. Kanat O, Evrensel T, Kurt E, Arslan M, Demiray M, Aker S, Manavoglu O. Successful treatment of thymoma-associated erythroid hypoplasia and thrombocytopenia with paclitaxel. Clin Oncol (R Coll Radiol). 2005 Feb;17(1):68
A17. Tasdelen I, Gokgoz S, Paksoy E, Yerci O, Cetintas SK, Demiray M, Samsa V. Acquired lymphangiectasis after breast conservation treatment for breast cancer: report of a case. Dermatol Online J. 2004 Jul 15;10(1):9.
A18. Ozkan K, Turkkan E, Ender K, Mutlu D, Murat A, Nalan B, Abdulmecit Y, Osman M. 5-Fluorouracil, epirubicin and cisplatin in the treatment of metastatic gastric carcinoma: a
retrospective analysis of 68 patients. Indian J Cancer. 2005 Apr-Jun;42(2):85-8.
B. Papers presented at international scientific meetings and published in the proceedings book
(Proceedings)
B1. Demiray M, Sahinbas H. Hyperthermia , Chemotherapy and Curcumin treatment modality is safe and may be more effective strategy for cancer treatment. V. Hyperthermia Symposium Köln 3-4 october (kabul edildi)
B2. Demiray M, Manavoglu O, Evrensel T, Tasdelen I, Tolunay S, Kurt E, Kanat O, Gonullu
G. The response rates of two different dosages of epirubicin in neoadjuvant chemotherapy of locally advanced breast cancer: High dose vs low dose ? ASCO 2003 Proc Am Soc Clin Oncol 22: page 81, 2003 (abstr 322)
B3. Demiray M, Gülten M, Kurt E, Evrensel T, Kanat O, Ulukaya E, Gonullu G, Manavoglu O. Relationship of Helicobacter Pylori status and gastric epithelial proliferation. 11th World
Congress of surgeons&gastroenterologists, Hepato-Gastroenterology, 2001;48(suppl 1): p108.
B4. Demiray M, Kurt E, Gülten M, Evrensel T, Kanat O, Izgi B, Gonullu G, Manavoglu O.Relationship of Helicobacter Pylori status and serum selenium and malondialdehyde levels. 11th World Congress of surgeons&gastroenterologists, Hepato-Gastroenterology,  2001;48(suppl 1): p109.
B5. Gonullu G, Kurt E, Evrensel T, Demiray M, Kanat O, Yilmazlar T, Manavoglu O. Our treatment results of rectum melanoma. 11th World Congress of surgeons&gastroenterologists,
Hepato-Gastroenterology 2001;48(suppl 1): p144.
B6. Gonullu G, Kurt E, Evrensel T, Kanat O, Demiray M, Yerci O, Manavoglu O Primary gastric lymphomas: Clinical features and results of therapy.. 11th World Congress of surgeons&gastroenterologists, Hepato-Gastroenterology 2001;48(suppl 1): p145.
B7. Kanat O, Kurt E, Evrensel T, Demiray M, Gonullu G, Manavoglu O. Malignant gastrointestinal tumors: Clinical features and results of therapy. 11th World Congress of surgeons&gastroenterologists, Hepato-Gastroenterology 2001;48(suppl 1): p142.
B8. Kurt E, Kanat O, Evrensel T, Demiray M, Arslan M, Gonullu G, Manavoglu O. A phase II study of gemcitabine plus 5-fluorouracil in patients with advanced pancreatic cancer. 11th World Congress of surgeons&gastroenterologists, Hepato-Gastroenterology 2001;48(suppl 1):  p132.
B9. Kurt E, Evrensel T, Dilek K, Filiz G, Gonullu G, Kanat O, Arslan M, Demiray M, Manavoglu O. Effects of two different doses of recombinant human erythropoietin (rHuEPO) on cisplatin-induced acute renal failure. Program/Proceedings, ASCO-ThirtyEighth Annual Meeting, May 18-21, 2002, Orlando, FL, P1842. B10. Arslan M, Kurt E, Evrensel T, Gonullu G, Kanat O, Demiray M, Ali R, Manavoglu O. Comparison of the serum erythropoietin levels in chemotherapy-naïve and cisplatin-treated cancer patients. 27th ESMO Congress, 18-22 October, 2002, Nice-France. P73.
B11. T. Gulten, M. Demiray, İ. Ercan, M.Gülten, R. Tokyay. Standart eradication therapy reduces the DNA damage in Helicobacter pylori infected patient. Eurosurgery 2000, İstanbul,
2000
B12. Kurt E, Demiray M, Kanat O, Evrensel T, Arslan M, Gonullu G, Yilmazlar T, Manavoglu O. Gastrointestinal cancers associated with other primary cancers. 11th World Congress of surgeons&gastroenterologists, Hepato-Gastroenterology 2001;48(suppl 1): p133.
B13. Gonullu G, Kurt E, Evrensel T, Kanat O, Demiray M, Tasdelen I, Manavoglu O. Neoadjuvant chemotherapy for breast cancer: Results of a single institute experience. 27th ESMO Congress, 18-22 October, 2002, Nice-France. P226
B14. Kanat O, Kurt E, Evrensel T, Demiray M, Ozkan A, Gonullu G, Manavoglu O. Fluorouracil, Epirubicin and Cisplatin (FEP) in locally advanced or metastatic gastric cancer.
12th World Congress of International Association of Surgeons&Gastroenterologists, October 30-November 2, 2002, Istanbul. PP339.
B15. Gonullu G, Kurt E, Evrensel T, Kanat O, Demiray M, Manavoglu O. Clinical features and treatment result of gastrointestinal system (GIS) lymphoma. 12th World Congress of International Association of Surgeons&Gastroenterologists, October 30-November 2, 2002, Istanbul. PP353.
B16. Gonullu G, Kurt E, Evrensel T, Demiray M, Kanat O, Manavoglu O. FEP regimen in the treatment of hepatocellular and biliary tract carcinoma. 12th World Congress of International
Association of Surgeons&Gastroenterologists, October 30-November 2, 2002, Istanbul. PP348.
B17. Gonullu G, Kurt E, Evrensel T, Kanat O, Demiray M, Arslan M, Kiyici M, Yilmazlar T, Manavoglu O. Second-Line 5-fluorourocil+folinic acid+irinotecan chemotherapy in colorectal cancer patients. 12th World Congress of International Association of Surgeons&Gastroenterologists, October 30-November 2, 2002, Istanbul. PP347.
B18. Tuna Gülten, Tokyay N, Demiray M, Ercan I, Evke E, Gülten M, Sardas S, Karakaya E.A. The role of age, gender and smoking on helicobacter pylori’s genetoxic effect and on the
efficacy of the eradication therapy. Europan Human Genetics Conference 2000.
B19. Yakut T, Demiray M, Çalışkan Z, Gülten T. HER2/neu gene amplification in muscle invasive bladder cancer; FISH analysis on paraffin-embedded specimens. EUROPEAN HUMAN GENETICS CONFERENCE 2005 Center, Prague, Czech Republic May 7 - 10, 2005. P0533.
B20. Kanat O, Evrensel T, Kurt E, Baran I, Coskun H, Demiray M, Gonullu G, Turan O.F, Zarifoglu M, Arslan M, Manavoglu O. Protective effect of amifostine against toxicity of paclitaxel/carboplatin regimen in non-small cell lung cancer. Program/Proceedings, ASCOThirty-Eighth Annual Meeting, May 18-21, 2002, Orlando, FL, P2774. D. Articles published in national refereed journals
D1. Demiray M, Evrensel T, Arslan M, Kanat O, Kurt E, , Saraydaroglu O, Ercan I, Gokgoz S, Topal U, Tolunay S, Tasdelen I, Manavoglu O. Phase II study of gemcitabine plus epirubicin plus paclitaxel in metastatic breast cancer patients. Turkish Journal Of Cancer 2005, Volume 35, Number 4, Page(s) 159-165
D2. Demiray M, Evrensel T, Kanat O, Kurt E, Arslan M, Saraydaroglu O, Ercan I, Gonullu G, Gokgoz S, Tolunay S, Gozkaman A, Akgul N, Tasdelen I, Manavoglu O. The Efficacy Of Two Different Dosages Of Epirubicin In Neoadjuvant Setting: Fec50 Vs Fec100.Preliminary Report. Turkish Journal Of Cancer 2005, Volume 35, Number 1, Page(s) 019-025
D3. Demiray M, Manavoğlu O. Helicobacter pylori ve gastrik karsinogenez. Uludağ Üniversitesi Tıp Fakültesi Dergisi 29 (2) 29-33, 2003.
D4. Kurt E, Evrensel T, Dilek K, Gönüllü G, Kanat Ö, Demiray M, Arslan M, Ünlü Ö, Manavoğlu O. Cisplatin’e bağlı böbrek toksisitesi ve sentetik oral prostaglandin E1 analoğunun etkinliğinin değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 28(2):17-20,2002
D5. Kanat Ö, Evrensel T, Kurt E, Demiray M, Arslan M, Gönüllü G, Babacan N, Yıldız A, Manavoğlu O. 5-Fluorouracil, epirubicin, and cisplatin (FEP) in the treatment of gastric carcinoma. Turkish Journal of cancer 2004, Volume 34, Number 3, Page(s) 122-126
D6. Kanat Ö, Evrensel T, Bayram S, Tolunay Ş, Kurt E, Demiray M, Gönüllü G, Kahvecioğlu S, Gebitekin C, Manavoğlu O. Timoma: On bir olgunun retrospektif analizi. Bursa Devlet
Hastahanesi Bülteni 18(1): 19-23, 2002
D7. Gönüllü G, Erdoğan C, Evrensel T, Kurt E, Demiray M, Arslan M, Kanat Ö, Ursavaş A, Gözkaman A, Manavoğlu O. Vena kava süperior sendromunda endovasküler tedavi
yönteminin etkinliği. Bursa Devlet Hastahanesi Bülteni 19(3): 139-143, 2004
D8. Gönüllü G, Evrensel T, Kurt E, Bayram S, Demiray M, Kanat Ö, Arslan M, Gözkaman A, Altundal Y, Manavoğlu O. Evre III Küçük hücreli dışı akciğer kanserinde (KHDAK) neoadjuvant gemsitabin ve sisplatin kombinasyonunun etkinliğinin değerlendirilmesi. Bursa Devlet Hastahanesi Bülteni 19(1): 31-34, 2004
D9. Kanat O, Evrensel T, Tolunay S, Demiray M, Gönüllü G, Kurt E, Manavoğlu O. Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid gland: Description of a case and review of the literature. 2004, Volume 34, Number 3, Page(s) 122-126
D10. Kanat Ö, Evrensel T, Demiray M, Gönüllü G, Kurt E, Filiz G, Manavoğlu O. Uzun süreli tam remisyondaki küçük hücreli mesane karsinomlu olguda izole beyin metastazı.
THOD 2003, vol 13, num 3 page(s): 153-156
D11. Kurt E, Evrensel T, Arslan M, Filiz G, Gönüllü G, Kanat Ö, Demiray M, Manavoğlu O. Eş zamanli olarak saptanan dört primer kanserli olgu. THOD 2002, Vol 12, Num 3
Page(s): 157-161
D12. Gönüllü G, Evrensel T, Kurt E, Kanat O, Demiray M, Arslan M, Yılmazlar S, Yalçın R, Adım Ş, Gözkaman A, Manavoğlu O. İntrakraniyal yerleşimli germ hücreli tümör olgusu. Bursa Devlet Hastanesi Bülteni 2004 19(2) s99-104
D13. Gönüllü G, Kurt E, Evrensel T, Adım Ş, Demiray M, Kanat O, Özgüç H, Manavoğlu O. Rektum kanseri ve cilt metastazı. Bursa Devlet Hastanesi Bülteni 2002 18(1) s57-62
E. Papers Presented In National Scientific Meetings And Published In Proceedings
E1. Demiray M, Ulukaya E, Arslan M, Yılmaztepe A, Saraydaroğlu Ö, Gökgöz Ş, Evrensel T, Manavoğlu O. Serum apoptosis düzeyi meme kanserinin neoadjuvan kemoterapiye yanıtında markır olabilirmi? XVI. Ulusal Kanser Kongresi Antalya 2005
E2. Demiray M, Evrensel T, Gökgöz Ş, Arslan M, Saraydaroğlu Ö, Topal U, Taşdelen İ, Manavoğlu O.Neoadjuvan FEC ile Epirubisin+Dozetaksel kombinasyonlarının etkinliğinin karşılaştırılması: Prospektif Randomize çalışma. XVI. Ulusal Kanser Kongresi Antalya 2005
E3. Demiray M, Manavoğlu O, Evrensel T, Taşdelen İ, Tolunay Ş, Kurt E, Kanat O, Gönüllü G. Meme kanserinin neoadjuvan kemoterapisinde antrasiklin doz intensitesi cevabı etkiliyor
mu? XV. Ulusal Kanser Kongresi Antalya, 2003.
E4. Dane Ediger, Mutlu Demiray, Esra Uzaslan, Mehmet Karadağ, Esra G. Yüksel, Nihat  Özyardımcı. Atipik pnömoni ile ortaya çıkan yaygın değişken immune yetmezlik sendromu
olgusu. 25. Yıl Akciğer Günleri 2000. .
E5. Demiray M, Evrensel T, Kanat O, Gebitekin C, Kurt E, Gönüllü G, Demiray H, Manavoğlu O. Sistemik Sitotoksik ve non-sitotoksik tedavi ile cevap alınan desmoid tümör olgusu. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S177 (P1501)
E6. Demiray M, Demiray H, evrensel T, Kurt E, Kanat Ö, Gönüllü G, Akıncıoğlu Ç, Akbunar T, Manavoğlu O. Meme kanserindeki kemik metastazlarında alkalen fosfatazın prediktif  değeri. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S134 (P362).
E7. Süleymanlar İ, Altınayak R, Demiray M, Özben T, Işıtan F. Kronik karaciğer hastalıklarında parankim hasarının göstergesi olarak plazma fibronektin düzeyi. XI. Ulusal Türk gastroenteroloji Kongresi 1994 Antalya
E8. Kanat Ö, Kurt E, Evrensel T, Arslan M, Gönüllü G, Demiray M, Manavoğlu O. NSCLC  olgularında sekond line kemoterapi sonuçlarımız. Ulusal Kanser kongresi İstanbul 2001 Bildiri Özetleri S74 (SB10)
E9. Gönüllü G, Evrensel T, Kurt E, Kanat O, Demiray M, Arslan M, Manavoğlu O. Lokal ileri meme kanserinde primer kemoterapi sonuçlarımız. Ulusal Kanser kongresi İstanbul 2001  Bildiri Özetleri S118 (PO-1ME)
E10. Kurt E, arslan M, Evrensel T, Demiray M, Kanat O, Gönüllü G, Manavoğlu O. Multipl primer kanserli hastalarımızın analizi. Ulusal Kanser kongresi İstanbul 2001 Bildiri Özetleri S131 (PO-4)

E11. Evrensel T, Kanat O, Kurt E, Gönüllü G, Demiray M, Manavoğlu O. Primer gastrik lenfomalı hastalarımızın analizi. Ulusal Kanser kongresi İstanbul 2001 Bildiri Özetleri S186 (PO-5)
E12. Evrensel T, Kurt E, Kanat O, Gönüllü G, Demiray M, Arslan M, Yılmazlar T, Öztürk H, Manavoğlu O. Primer karaciğer lenfoması: Vaka sunumu. Ulusal Kanser kongresi İstanbul 2001 Bildiri Özetleri S186 (PO-5)
E13. Kanat O, evrensel T, Özkan A, Demiray M, Kurt E, Gönüllü G, Manavoğlu O. Yetmiş yaş üzeri küçük hücreli dışı akciğer kanserli olgulada cisplatin ve etoposide kombinasyon tedavisinin etkinliği. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S23 (P004)
E14. Demircan C, Evrensel T, Özkan L, Ursavaş A, Özkan A, Özcan V, Kurt E, Gönüllü G, Demiray M, Manavoğlu O. Acil servise başvuran akciğer kanserli hastaların analizi. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S32 (P033)
E15. Gönüllü G, Kurt E, Evrensel T, Kanat O, Demiray M, Arslan M, Gözkaman A, Manavoğlu O. Mide kanserinde second-line irinotekan monoterapisi: Klinik sonuçlarımız. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S83 (P192)
E16. Kanat O, Evrensel T, Demiray M, Balaban Adım Ş, vuruşkan H, Kurt E, Gönüllü G, Manavoğlu O. Olgu sunumu: Renal hemanjioperisitoma. Ulusal Kanser kongresi Antalya 2003 Bildiri Özetleri S177 (P1500)