MEDICAL SECOND OPINION

Medical School

Selcuk University, Meram Faculty of Medicine, 2004 

Post-Graduate Training

Gynecology And Obstetrics and Perinatology Specialist, Zekai Tahir Burak Women's Health Training and Research Hospital, 2012


Professional Experience
Zekai Tahir Burak Women's Health Training and Research Hospital, Department of Gynecology and Obstetrics 2007-2012
Zekai Tahir Burak Women's Health Training and Research Hospital, Department of Perinatology, 2013-2016 
Selcuk University, Selcuklu Faculty of Medicine, Department of Perinatology, 2019-2021
Medicana Konya Hospital, 2021-current


Special Experience

Perinatology 
Pregnancy and High-Risk Pregnancy Tracking
Laparoscopic Operations
Hysteroscopy Operations
Gynecological Operations
Infertility Follow-up and Treatment
Urinary Incontinence Operations
TOT, TVT, Cystorectocele.
Aesthetic Operations

Medical Interests
Early diagnosis of fetal anomalies
Chromazole anomaly scan
Predicting and preventing preeclampsia
Cervical insufficiency management (cervical cerclage)
Management of fetal growth retardation
Management of gestational diabetes
Follow-up of multiple pregnancies
Detailed fetal ultrasonography 4D ultrasonography (4D USG)
Amniocentesis Cordocentesis
Chorionic villus sampling
Intrauterine Fetal Blood Transfusion
Management of placental adhesion anomalies
Genital Aesthetics (Hymenoplasty - Labiaplasty)
Laparoscopic Surgery (Closed Uterus and Ovary)
Infertility (Infertility Treatment)
Urogynecology (Medical and Surgical Treatment of Urinary Incontinence, Uterine Prolapse)
4D Ultrasonography
Normal Birth, Water Birth (VBAC)
Recurrent Pregnancy Loss Tracking
Hysteroscopy Procedures
Genital Aesthetics
Genital Whitening
PRP and Stem Cell Application to the Genital Area
Vaginal Dryness for Menopausal Patients
PRP and Stem Cell Applications
PRP in Recurrent and Resistant Vaginal Discharges
Mesotherapy and Stem Cell Application

Academic Publications:
Özler S, Öztaş E, Tokmak A, Ergin M, Kuru Pekcan M, Gümüş Güler B, Yakut Hİ, Yılmaz N.Role of Versicanand ADAMTS-1 in Polycystic Ovary Syndrome. J Clin Res Pediatr Endocrinol. 2017 Mar 1;9(1):24-30. doi: 10.4274/jcrpe.3414. 
Ozler S, IsciBostanci E, Oztas E, Kuru Pekcan M, GumusGuler B, Yilmaz N.The role of ADAMTS4 and ADAMTS9 in cardiovasculardisease in premature ovarian insufficiency and idiopathic hypogonadotropic hypogonadism. J 
EndocrinolInvest. 2018 Dec;41(12):1477-1483. doi: 10.1007/s40618-018- 0948-3. 
3. Bostanci EI, Ozler S, Yilmaz NK, Yesilyurt H.Serum 25-Hydroxy Vitamin D Levels in Turkish Adolescent Girls with Polycystic Ovary Syndrome and the Correlation with Clinical/Biochemical Parameters. J Pediatr Adolesc Gynecol. 2018 Jun;31(3):270-273. doi: 10.1016/j.jpag.2017.07.008. 
4 Oztas E, Ozler S, Caglar AT, Yucel A.Analysis of first and second trimester maternal serum analytes for the prediction of morbidly adherent placenta requiring hysterectomy. Kaohsiung J MedSci. 2016 Nov;32(11):579-585.doi: 10.1016/j.kjms.2016.08.011. 
5. Kadıoğlu N, Güler B, Özler S, Kılıç S, Çiçek MN, Batıoğlu AS.OvulationInduction is a More Effective Stimulant on Antiovarian Antibody Production than In Vitro Fertilization. Adv Ther. 2016 Aug;33(8):1408-16. doi: 10.1007/s12325-016-
0356-z. 
6. Ersoy AO, Tokmak A, Ozler S, Oztas E, Ersoy E, Celik HT, Erdamar H, Yilmaz N. Are progranulin levels associated with polycystic ovarysyndrome and its possible metabolic effects in adolescents and young women?. Arch Gynecol Obstet. 2016 Aug;294(2):403-9. doi: 10.1007/s00404-016-4096-8. 
7. Ersoy E, Ersoy AO, Yasar Celik E, Tokmak A, Ozler S, Tasci Y.Is it possible to prevent striae gravidarum?. J ChinMedAssoc. 2016 May;79(5):272-5. doi: 10.1016/j.jcma.2015.12.007. 
8. Ersoy AO, Oztas E, Ozler S, Ersoy E, Erkenekli K, Uygur D, Caglar AT, Danisman N. Can venouspro-BNP levels predict placenta accreta?.J Matern Fetal Neonatal Med. 2016 Dec;29(24):4020-4. doi: 10.3109/14767058.2016.1152576. 
9. Oztas E, Ozler S, Tokmak A, Yilmaz N, Celik HT, Kazancı FH, Danisman N, Ergin M, Yakut HI.Increasedlevels of serum granzyme-B is associated with insulin resistance and increased cardiovascular risk in adolescent polycystic ovary syndrome patients. Eur J Obstet Gynecol Reprod Biol. 2016 Mar;198:89-93. doi: 10.1016/j.ejogrb.2016.01.009. 
10. Ozler S, Oztas E, Caglar AT, Uygur D, Ergin M, Erel O, Danisman N.Thiol/disulfide homeostasis in predicting adverse perinatal outcomes at 24-28 weeks of pregnancy in gestational diabetes. J Matern Fetal Neonatal Med. 2016 Nov; 29(22) :3699-704. doi: 10.3109/14767058.2016.1141885. 
11. Ozler S, Erel O, Oztas E, Ersoy AO, Ergin M, Sucak A, Neselioglu S, Uygur D,  Danisman N. Serum Thiol/Disulphide Homeostasis in Preeclampsia. Hypertens Pregnancy. 2015 Nov;34(4):474-485. 
12. Ozler S, Oztas E, Tokmak A, Ergin M, Isci E, Eren F, Pehlivan S, Neselioglu S, Yılmaz N. The association of thiol/disulphide homeostasis and lipid accumulation index with cardiovascular risk factors in overweight adolescents with polycysticovarysyndrome.ClinEndocrinol (Oxf). 2016 Apr;84(4):516-23. Doi: 10.1111/cen.12965. 
13. Oztas E, Ozler S, Ersoy AO, Erkenekli K, Sucak A, Ergin M, Uygur D, Danisman N.Placental ADAMTS-12 Levels in thePathogenesis of PreeclampsiaandIntrahepaticCholestasis of Pregnancy.ReprodSci. 2016 Apr;23(4):475-81. Doi: 10.1177 /1933719115604730. 
14. Oztas E, Ozler S, Ersoy AO, Iskender CT, Sucak A, Ergin M, Uygur D, Danisman N.Increasedlevels of serum clusterin is 
Associated with intrauterine growth restriction and adverse pregnancy outcomes in preeclampsia.J PerinatMed. 2016 Apr;44(3):269-75. Doi: 10.1515/jpm2015-0120. 
15. Oztas E, Erkenekli K, Ozler S, Aktas A, Buyukkagnıcı U, Uygur D, Danisman N. First trimester interleukin-6 levels help to predict adverse pregnancy out comes in both thyroid auto antibody positive and negative patients .J ObstetGynaecolRes. 
2015 Nov;41(11):1700-7. Doi: 10.1111/jog.12799. 
16. Ersoy AO, Oztas E, Ersoy E, Ozler S, Ergin M, Yilmaz N. Granulin levels in Patients with idiopathic prematüre ovarian failure. Eur J Obstet Gynecol Reprod Biol. 2015 Oct;193:108-10. Doi: 10.1016/j.ejogrb.2015.07.015. 
17. Oztas E, Ozler S, Ersoy E, Ersoy AO, Tokmak A, Ergin M, Uygur D, Danisman N.Prediction of gestational diabetes mellitusby first trimester serum secretedfrizzle-related protein-5 levels.J MaternFetalNeonatalMed. 2016;29(9):1515-9. Doi: 10.3109/14767058.2015.1052399. 
18. Ozler S, Oztas E, Uygur D, Ersoy AO, Ergin M, Koca C, Danisman N, Erkaya S.The Value of Total antioxidantStatusand Serum TumorNecrosisFactor-α Levels at 24-28 Weeks of Gestation in thePrediction of Optimal Treatment Protocol in GestationalDiabetesMellitus.ExpClinEndocrinolDiabetes. 2019 Jul;127(7):485-491. Doi: 10.1055/s-0035-1554623. 
19. Ersoy AO, Kirbas A, Ozler S, Ersoy E, Ozgu-Erdinc AS, Ergin M, Erkaya S, Uygur D, Danisman N.Maternalandfetal serum levels of caspase-cleaved fragments of cytokeratin-18 in intrahepatic cholestasis of pregnancy.J Matern Fetal Neonatal Med. 2016;29(4):562-6. Doi: 10.3109/14767058.2015.1011116. 
20. Oztas E, Erkenekli K, Ozler S, Ersoy AO, Kurt M, Oztas E, Uygur D, Danisman N.Can routine laboratory parameters predict adverse pregnancy  outcomes in İntrahepati cholestasis of pregnancy?J PerinatMed. 2015 Nov;43(6):667-74. 
Doi: 10.1515/jpm-2014-0207. 
21. Ersoy AO, Unlu S, Oztas E, Ozler S, Uygur D, Yucel A. Influenza infections in the 2014–2015 season and pregnancy outcomes. J Infect Dev Ctries 2017; 11(10):766-771. Doi:10.3855/jidc.8461 
22.  Ozyer S, Uzunlar O, Ozler S, Kaymak O, Baser E, Gungor T, Mollamahmutoglu L. Awareness of Turkish female adolescents and young women about HPV And their attitudes towards HPV vaccination. AsianPac J CancerPrev. 
2013;14(8):4877-81.Oztas E, Ozler S, Ersoy AO, Ersoy E, Caglar AT, Uygur D, Yucel A, Ergin M, 52 Danisman N.Decreased placental andmaternal serum TRAIL-R2 levelsareassociatedwithplacentaaccreta.Placenta. 2016 Mar;39:1-6. Doi: 
10.1016/j.placenta.2016.01.004. 
24. Ozler S, Demircan K.Theinvestigation of the role of proteoglycans and ADAMTS levels in fetalmembranes in physiopathological process of gestational diabetes. Med Hypotheses. 2017 Jul;104:182-184. Doi: 10.1016 /j.mehy. 2014. 06.020. 
25. Ozler S, Oztas E, Guler BG, Ergin M, Uygur D, Yucel A, Erel O, Danisman N. ADAMTS4 and Oxidative/Antioxidative Status in Preterm Premature Rupture of Membranes.Fetal Pediatr Pathol. 2016;35(4):239-50. Doi: 10.1080/15513815. 2016.11755 29.  
26. Ozler S, Oztas E, Guler BG, Pehlivan S, Kadioglu N, Ergin M, Uygur D, Danisman N.Role of ADAMTS5 in Unexplained Fetal Growth Restriction (FGR).Fetal Pediatr Pathol. 2016;35(4):220-30. Doi: 10.3109/15513815.2016.1173146. 
27. Ozler S, Oztas E, Erel O, Guler BG, Ergin M, Uygur D, Danisman N.Impact of Gestational Diabetes Mellitus and Maternal Obesity on Cord Blood Dynamic Thiol/Disulfide Homeostasis. Fetal Pediatr Pathol. 2017 Feb;36(1):8-15. Doi: 10.1080/ 15513815.2016.1223237. 
28. Gumus Guler B, Ozler S. Increasedlevels of serum serglycin and agrin is associated with adverse perinatal outcome in early onset preeclampsia. Fetal Pediatr Pathol. 2019 Apr 24:1-14. Doi: 10.1080/15513815.2019.1604922. 
29. Sibel Ozler, Efser Oztas, Aysegul Kebapcilar, Ali Turhan Caglar. The role of thyroid-stimulating hormone and thyroglobulin antibody in abnormally invasive placenta. J Matern Fetal Neonatal Med. 2021 Jan 21;1-9.doi: 
10.1080/14767058.2021.1875430 
30. Öztaş E, Özler S, Ergin M, Erel Ö, Gümüş Güler B, Çağlar AT, Yücel A, Uygur D, Danışman N. Decreased oxidative stress may contribute to the disease process in placenta accreta. Turk J MedSci. 2017 Aug 23;47(4):1180-1184. Doi: 
10.3906/sag-1605-141. 
31. Ozler S, Oztas E, Guler BG, Ersoy AO, Ergin M, Uygur D, Danisman N.3Ds: decorin, discordance, and diamniotic dichorionictwins.ClinExpObstetGynecol. 2017;44(2):239-243. 
32. Oztas E, Ozler S, Tokmak A, Erel O, Ergin M, Uygur D, Danisman N.Oxidativestressmarkers in severe preeclampsia and preeclampsia-related perinatal morbidity –preliminary report.GinekolPol. 2016;87(6):436-41. Doi:10.5603/GP.2016.0022. 
33. Ersoy AO, Ozler S, Oztas E, Ersoy E, Kirbas A, Danisman 
N. The association between placenta previa and leukocyte and platelet indices – a Case control study.GinekolPol. 2016;87(5):367-71. Doi: 10.5603/GP.2016.0006. 52
34. Ersoy AO, Ozler S, Oztas E, Ersoy E, Ergin M, Erkaya S, Uygur D.The Association between N-terminal Pro-Brain Natriuretic Peptide Levels in The Umbilical Vein and Amniotic Fluid Volume Abnormalities.RevBrasGinecolObstet. 2016 Apr;38(4):177-82. Doi: 10.1055/s0036-1583172. 
35. Güler B, Özler S, Kadıoğlu N, Özkan E, Güngören MS, Çelen Ş.Is thelow AMH Level associated with the risk of cardiovascular disease in obese pregnants?J Obstet Gynaecol. 2020 Oct;40(7):912-917. Doi: 10.1080/ 01443615 .2019. 1672633. Epub 2019 Dec 6. 
36 Ozler S, Oztas E, Guler BG, Caglar AT. Increasedlevels of serum IL-33 is Associated with adverse maternal  outcomes in placenta previa accreta.J Matern Fetal Neonatal Med. 2019 Oct 24:1-8. Doi: 10.1080/14767058.2019.1679766. 
37.  Ozler S, Oztas E, GumusGuler B, Erel O, Turhan Caglar A, Ergin M, Uygur D, Danisman N.Are serum levels of ADAMTS5, TAS and TOS at 24-28 Gestational weeks associated with adverse perinatal outcomes in Gestational diabetic women?J Obstet Gynaecol. 2020 Jul;40(5):619-625. Doi: 10.1080/01443615.2019.1634025. Epub 2019 Sep 17. 
38 Ersoy AO, Oztas E, Ozler S, Tokmak A, Ersoy E, Ergin M, Danisman N. Maternal venous SHARP1 levels in preeclampsia. 
J Perinat Med. 2017 Oct 26;45(7):803-808. Doi: 10.1515/jpm-2015-0437. 
39 Ozler S, Oztas E, Guler BG, Erel O, Caglar AT, Ergin M, Danisman N. Dynamic Thiol/Disulfide Homeostasis in Predicting Adverse Neonatal Outcomes in Fetal  Growth Restriction. Fetal Pediatr Pathol. 2020 Apr;39(2):132-144. Doi:10.1080 /15513815.2019.1644686. 
40 Ersoy E, Özler S, Öztaş E, Ersoy AÖ, Ergin M, Tokmak A, Yilmaz N. Comparison of Serum A Disintegrin and Metalloproteinase with Thrombospondin Motifs-19 Levels in Different Fertility Situations: CouldIt Be a Serum Marker of 
Ovarian Function and Oocyte Pool? Gynecol Obstet Invest. 2019;84(1):6-11. Doi: 10.1159/000490665. Epub 2018 Jul 6. 
41. Gümüş Güler B, Özler S. Increased syndecan-1 and glypican-3 Predict poor perinatal outcome and treatment resistance in İntrahepatic cholestasis. Hepatobiliary Pancreat DisI nt. 2020 Jun;19(3):271-276. Doi: 10.1016/j.hbpd.2019.12.001. Epub 2019 Dec 14 
42.  Kozanhan B, Bardak O, Sami Tutar M, Ozler S, Yildiz M, Solak I. The influence  of Body Roundness Index on sensorial block level of  spinal anaesthesia for elective caesarean section: an observational study. J  ObstetGynaecol. 2020 Aug; 40(6): 772-778. Doi: 10.1080/01443615.2019.1647523.ÖZTAŞ
43. Ozler S, Ersoy AO, Oztas E, Topcu V, Celen S, Danisman N.The unprecedented recurrent diploid/tetraploid mosaicism of trisomy-18 (mixoploidy; 4n+18/2n+18): clinical report.Am J Med Genet A. 2015 Jul;167(7):1650-3. Doi: 10.1002 /ajmg.a. 37062.
44. Güler B, K Nezaket, Özler S, Sarıkaya E, Çiçek MN, Ergün A, Batıoğlu S. Antiovarian Antibody may be Used as A Predictor for Poor In Vitro Fertilization Outcome. Journal of Reproductive Endocrinology&Infertility. 2016;1:2-9. Doi: 10.4172/JREI.100009. 
45. Deniz ÇD, Özler S, Sayın FK, Eryılmaz MA. Associations between night eating syndrome and metabolic parameters in 
Pregnant women.Turk J Obstet Gynecol. 2019 Jun;16(2):107-111. Doi: 10.4274/tjod.galenos.2019.77864. 
46. Ersoy AO, Oztas E, Saridogan E, Ozler S, Danisman N. An Unusual Origin of Fetal Lymphangioma Filling Right Axilla. J Clin Diagn Res. 2016 Mar;10(3):QD09-11. Doi: 10.7860/JCDR/2016/18516.7513.
47. Ersoy AÖ, Topçu V, Kale İ, Ersoy E, Özler S, Danışman N.A Novel mutated sequence in the T-box transcription factor-5 (TBX-5) gene (c.241A>T) in Holt-Oram syndrome.J Turk Ger Gynecol Assoc. 2015 Jul 14;17(1):55-7. Doi: 10.5152/jtgga.2015.15233.
48.  Ersoy AÖ, Özler S, Göllü BG, Ersoy E,Danısman N. Fetus İn Fetu A Rare Prenatal Diagnosis Of A Fetal Abdominal Mass. West Indian Med J DOI: 10.7727/Wimj.2015.314
49. Deniz Çiğdem Damla, Kozanhan Betül, Tutar Mahmut Sami, Özler Sibel. Üçlü test ile ilgili internet bilgilendirme metinlerinin okunabilirlik ve içeriklerinin değerlendirilmesi. Mersin Üniversitesi Sağlık Bilimleri Dergisi, 2020;35-44., Doi: 10.26559/mersinsbd.569617. 
50.  Özler Sibel, Güler Gümüş Başak. Does the measurement of the size of The first trimester subchorionic hematoma by 2D and 3D Ultrasonographic techniques have any effect on Adverse pregnancy outcomes?.Archives of Clinical and Experimental Medicine, 2019; 4(3), 122-126., Doi: 10.25000/acem.586513. 
51.  Özler Sibel, Güler Gümüş Başak. Twin pregnancy outcome of our clinic: A three- year followup. Annals of Medical Research, 2019;26(12), 2892, Doi: 10.5455/annalsmedres.2019.08.484. 
52. Özler S, Öztas E, Güler GB, Yücel A,Uygur D. Maternal and perinatal effects of Vaginal delivery after caesarean section.Med-Science. 2016; 5(4): 957-60. 
53. Kadıoglu N, Özler S, Gulmez E, Güler GB, Patlakoglu E. Comparison of Liquid Based Cytology Results with Conventional Cytology Results in Screening Cervical Cancer.Med-Science. 2016; 5(4): 919-27. 
54.  Öztas E, Özler S, Solmaz D, SayganS,Uygur D, Çaglar At, Danısman AN. Can We Determine the Time Elapsed until the Birth in Preterm Premature Rupture of Membranes (Pprom) andPretermLabor (Pte)? [PretermPrematür Erken MembranRüptürü (Pprom) VePreterm Eylem (Pte)’De Doguma Kadar Geçen Süreyi Belirleyebilir Miyiz?].Med-Science. 2016; 5(2): 468-83 
55.  Ersoy AÖ, Özler S, Öztas E, Ersoy E, Kırbas A, Danısman AN. Are Leukocyte and Platelet Indices Associated with Small for Gestational Age Birth and/or Oligohydramnios?. Acta Medica Anatolia.2016;14-20. 
56.  Öztas E, Özler S, Bakır A,Savasçıoglu Kİ, Uygur D. Klinigimizin Üç Yıllık CVS Tecrübesi ve Sonuçları. İKSST Derg 8(2):81-87, 2016. 
57. Ersoy AÖ, Öztas E, Özler S, Ersoy E,Topçu HO, Fındık BR, Tasçı Y. Makrozomik Bebek Doguran Düsük Riskli Kadınların Gebelik Sonuçlarının Degerlendirilmesi. Journal of Clinical and Experimental Investigations. 2017;8:4. 
58. Gün EÖ, Yılmaz S, Özler S, Gülerman HC. Vajinal ve Sezaryen Dogumun Postpartum Servikal Yayma Sonuçlarına Etkisi. Fırat Tıp Derg/FiratMed J 2013; 18(3): 164-167. 
59.Erkeneklı K, Öztas E, Özler S,YücelA,Uygur D, Danısman N. Izole Intrauterin Gelisme Kısıtlılıgı Olan Gebeliklerde Tam Kan Sayım Parametreleri. Jinokoloji –Obstetrik ve Neonatoloji Tıp Dergisi 2015:12(1): 18 – 21. 
60. Ersoy E, Ersoy AÖ, Yasar ÇE, Özler S, Altay M, Gelısen O. Ultrasonografik Belirteçlerin Ilk Trimester Gebelik Sonuçlarını Öngörmedeki Rolü. Jinokoloji –Obstetrik ve Neonatoloji Tıp Dergisi 2015; 12: 2,75 – 79

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