MEDICAL SECOND OPINION

Medical School

Istanbul University Cerrahpaşa Faculty of Medicine (English Medicine), 2002


Post-Graduate Training

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, 2008


Professional Experience

Ankara University Faculty of Medicine, Department of Internal Medicine (Research Assistant), 2002-2003

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital (Cardiology Assistant), 2003-2008

Pendik State Hospital (Cardiology Specialist), 2009-2010

Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital (Cardiology Specialist), 2010-2012

Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital (Chief Resident), 2013-2016

Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital (Associate Professor), 2014-2016

Medical Park Bahçelievler Hospital (Associate Professor), 2016-2023

Medicana Ataköy Hospital, 2023-Present


Medical Areas of Interest

Echocardiography

Heart Valve Diseases

Heart Diseases in Pregnant Women

Adult Congenital Heart Diseases

Heart Failure

Pulmonary Hypertension

Hypertension

Dyslipidemia


Special Experience

Echocardiography

2D and 3D Transesophageal Echocardiography

Stress Echocardiography

Imaging in Perioperative/Invasive Procedures (MitraClip, TAVI, Paravalvular Leakage Closure)


Scientific publications

A. Articles Published in International Refereed Journals

A1. H.Unal Aksu, E.Oner, O.Celik, N.Isiksacan, H.Aksu, S.Uzun, D.Yavuz, S.Ozturk, M.Gul, N.Uslu. Aspirin Resistance in Patients Undergoing Hemodialysis and Effect of Hemodialysis on Aspirin Resistance. Clinical and Applied Thrombosis/Hemostasis (ISI), 2013. DOI: 10.1177/1076029613489597.

A2. H.Unal Aksu , E.Oner , M.Erturk, H.Aksu , N.Isıksacan , B.Ozalp, G.Akture , E.Akbay, L.Ozer , M.K.Erol. Aspirin resistance in patients with impaired renal functions. Kardiologia Polska (ISI), 2013.DOI: 10.5603/KP.a2013.0286.

A3. H.Ünal Aksu , N.Uslu , H.Aksu , Ö.F.Baycan , M.Ertürk , A.Eksik, M.Gül , F.B.Binbaş , M.K.Erol , İ.Bakır. The short-term outcomes of mitraclip implantation: Single-center experience in Turkey. Türk Göğüs Kalp Damar Cerrahisi Dergisi (ISI) , 2013 DOI: 10.5606/tgkdc.dergisi.2014.8622.

A4. H.U.Aksu , N.Uslu , M.Aslan , M.Gul , H.Aksu. Mitral Insufficiency Caused by Left Atrial Chordae. Echocardiography (ISI), e87-90 pp., 2012. DOI: 10.1111/j.1540-8175.2011.01599.

A5. H.U.Aksu , M.Ertürk , M.Gül , N.Uslu . Successful treatment of a patient with pulmonary embolism and biatrial thrombus. Anadolu Kardiyoloji Dergisi (ISI) , e13-14 pp., 2013; DOI: 10.5152/akd.2013.062.

A6. H.U.Aksu , K.Erkanlı , N.Uslu , İ.Bakır. Cardiac Mass of the Right Atrium: An Incidental Finding. Anadolu Kardiyol Derg. 2014 Jun;14(4):404, 410. doi: 10.5152/akd.2014.5230. Epub 2014 Jan 1.

A7. M.Erturk, H.U.Aksu, O.Celik, F.Uzun, O.Akgul, H.Pusuroglu, A.K.Kalkan, A.A.Yalcin, M.H.Satilmisoglu, M.K.Erol. Evaluation of the effect of mitral stenosis severity on the left ventricular systolic function using isovolumic myocardial acceleration. Cardiology Journal (ISI) , 2013. DOI: 10.5603/CJ.a2013.0114

A8. M.Erturk, M.Aslan, H.U. Aksu, İ.F.Akturk, M.Gul, F.Uzun, O.Surgit, H.Ari, N.Uslu, M.K.Erol. Evaluation of Atrial Electromechanic Delay and Left Atrial Mechanical Functions in the Patients with Secundum Type Atrial Septal Defect. Echocardiography (ISI) , 699-705 pp., 2013 , DOI: 10.1111/echo.12101

A9. O.Celik, M.M.Atasoy, M.Ertürk, A.A.Yalçin, H.U. Aksu, M.Diker, I.F.Aktürk,I.Atasoy. Single dose ivabradine versus intravenous metoprolol for heart rate reduction before coronary computed tomography angiography (CCTA) in patients receiving long-term calcium channel-blocker therapy. Acta Radiologica (ISI) , 2013 , DOI: 10.1177/0284185113505276

A10. M.Gul, H.Uyarel, O.Akgul, N.Uslu, A.Yildirim, A.Eksik, H.U. Aksu, E.Ozal, H.Pusuroglu, M.K.Erol, I.Bakir. Hematologic and Clinical Parameters After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Aortic Stenosis. Clinical and Applied Thrombosis/Hemostasis (ISI) , 2012 , DOI: 10.1177/1076029612462762

A11. M.Gul, H.Uyarel, M.Ergelen, M.Ugur, T.Isik, E.Ayhan, C.Turkkan, H.U.Aksu, O.Akgul, N.Uslu. Predictive Value of Neutrophil to Lymphocyte Ratio in Clinical Outcomes of Non-ST Elevation Myocardial Infarction and Unstable Angina Pectoris: A 3-Year Follow-Up. Clinical and Applied Thrombosis/Hemostasis (ISI), 2012, DOI: 10.1177/1076029612465669

A12. M.Gul, H.U.Aksu, K.Oz, I.Bakir. Rupture of the NovaFlex balloon during transcatheter aortic valve implantation and subsequent dissection of the right iliac arteries. European Journal Of Cardio-thoracic Surgery (ISI) , 437-38 pp., 2013

A13. M.Gül, S.Türen, O.Sürgit, H.U.Aksu, N.Uslu. Acute severe occlusion of the left main coronary artery following transcatheter aortic valve implantation. Anadolu Kardiyoloji Dergisi (ISI), 282-83 pp., 2012 , DOI: 10.5152/akd.2012.082

A14. H.Aksu, O.Ozer, H.Unal, G.Hobikoglu, T. Norgaz, A.Buturak, O.Soylu, A.Narin. Significance of mean platelet volume on prognosis of patients with and without aspirin resistance in settings of non-ST-segment elevated acute coronary

syndromes. Blood coagulation and fibrinolysis (ISI) , 686-93 pp., 2009 , DOI: 10.1097/MBC.0b013e32833161ac

A15. N.Sayar, A.Lütfullah Orhan, N.Cakmak, H.Yilmaz, H.Atmaca, B.Tangürek, H.Hasdemir, Z.Nurkalem, M.Ergelen, H.Aksu, K.Yeşilçimen. Correlation of the myocardial performance index with plasma B-type natriuretic peptide levels in patients with mitral regurgitation. The International Journal of Cardiovascular Imaging (ISI) , 151-57 pp., 2008

A16. Unal Aksu H, Gorgulu S, Diker M, Celik O, Aksu H, Ozturk D, Kırıs A, Kalkan AK, Erturk M, Bakır İ. Cardiac Computed Tomography versus Echocardiography in the Assessment of Stenotic Rheumatic Mitral Valve. Echocardiography. 2016 Mar;33(3):346-52. doi: 10.1111/echo.13076. Epub 2015 Sep 18.

A17. Satılmısoglu MH, Gorgulu S, Aksu HU, Aksu H, Ertaş G, Tasbulak O, Buturak A, Kalkan AK, Degirmencioglu A, Koroglu B, Tusun E, Murat A, Oz A. Safety of Early Discharge After Primary Percutaneous Coronary Intervention. Am J Cardiol. 2016 Jun 15;117(12):1911-6. doi: 10.1016/j.amjcard.2016.03.039. Epub 2016 Apr 6.

A18. Kalkan AK, Cakmak HA, Kalkan ME, Tuncer MA, Aydin E, Yanartas M, Satilmisoglu MH, Aksu HU, Erturk M, Gul M, Arslantas U, Kirali MK. The Predictive Value of Admission Fragmented QRS Complex for In-Hospital Cardiovascular Mortality of Patients with Type 1 Acute Aortic Dissection. Ann Noninvasive Electrocardiol. 2015 Sep;20(5):454-63. doi: 10.1111/anec.12232. Epub 2014 Nov 23.

A19. Yildirim A, Goktekin O, Gorgulu S, Norgaz T, Akkaya E, Aydin U, Unal Aksu H, Bakir I.A New Specific Device in Transcatheter Prosthetic Paravalvular Leak Closure: A Prospective Two-Center Trial. Catheter Cardiovasc Interv. 2016 Oct;88(4):618-624. doi: 10.1002/ccd.26439. Epub 2016 Feb 23.

A20. Öztürk D, Erturk M, Celık O, Ozyılmaz S, Akturk F, Cakmak HA, Aksu H, Pusuroglu H, Yalçın AA, Uslu N. The role of the neutrophil/lymphocyte ratio in patients with rheumatic mitral stenosis as an indicator of spontaneous echocardiographic contrast. Kardiol Pol. 2014;72(10):969-76. doi: 10.5603/KP.a2014.0093.

A21. Celik O, Atasoy MM, Erturk M, Yalcin AA, Aksu HU, Diker M, Akturk FI, Erkanli K, Atasoy I, Kiris A. Comparison of Different Strategies of Ivabradine Premedication for Heart Rate Reduction before Computed Tomography Coronary Angiography. J Cardiovasc Comput Tomogr. 2014 Jan-Feb;8(1):77-82. doi: 10.1016/j.jcct.2013.12.005. Epub 2014 Jan 9.

A22. Uslu N, Gul M, Cakmak HA, Atam A, Pusuroglu H, Satilmisoglu H, Akkaya E, Aksu HU, Kalkan AK, Surgit O, Erturk M, Aksu H, Eksik. The assessment of relationship between fragmented QRS complex and left ventricular wall motion score index in patients with ST elevation myocardial infarction who underwent primary percutaneous coronary intervention. A.Ann Noninvasive Electrocardiol. 2015 Mar;20(2):148-57. doi: 10.1111/anec.12180. Epub 2014 Jul 17.

A23. Ertürk M, Öner E, Kalkan AK, Püşüroğlu H, Özyılmaz S, Akgül Ö, Ünal Aksu H, Aktürk İF, Çelik Ö, Uslu. The role of isovolumic acceleration in predicting subclinical right and left ventricular systolic dysfunction in patient with metabolic syndrome. N. The role of isovolumic acceleration in predicting subclinical right and left ventricular systolic dysfunction in patient with metabolic syndrome.

A24. Erturk M, Buturak A, Pusuroglu H, Kalkan AK, Gurdogan M, Akturk IF, Akgul O, Aksu HU, Uzun F, Uslu N. Comparison of subclinical left and right ventricular systolic dysfunction in non-dipper and dipper hypertensives: impact of isovolumic acceleration. Clin Exp Hypertens. 2014;36(8):572-8. doi: 10.3109/10641963.2014.881844. Epub 2014 Feb 3.

A25. Erturk M, Cakmak HA, Surgit O, Celik O, Aksu HU, Akgul O, Gurdogan M, Bulut U, Ozalp B, Akbay E, Yildirim A. Predictive value of elevated neutrophil to lymphocyte ratio for long-term cardiovascular mortality in peripheral arterial occlusive disease. J Cardiol. 2014 Nov;64(5):371-6. doi: 10.1016/j.jjcc.2014.02.019. Epub 2014 Mar 28.

A26. Aksu HU, Aslan M, Ozturk D, Yalcin AA, Yıldırım A. Isolated cleft of both the anterior and posterior mitral valve leaflets. Echocardiography. 2016 Nov;33(11):1793-1794. doi: 10.1111/echo.13309. Epub 2016 Aug 22.

A27. Ertürk M, Aksu HÜ, Aktürk İF. Partial detachment of the mitral valvular ring: importance of three- dimensional transesophageal echocardiography.Anadolu Kardiyol Derg. 2014 Mar 19;14(3):E7. doi: 10.5152/akd.2014.5284.

A28. Uygur B, Ünal Aksu H, Eksik A. Rheumatic involvement of the cleft mitral valve. Anatol J Cardiol. 2016 Jun;16(6):460. doi: 10.14744/AnatolJCardiol.2016.7148.

A29. Uygur B, Ertürk M, Ünal Aksu H, Yıldırım A. Partial detachment of tricuspid valve annuloplasty ring detected by three-dimensional transesophageal echocardiography. Anatol J Cardiol. 2016 May;16(5):E9. doi: 10.14744/AnatolJCardiol.2016.7118.


B. Papers Presented at International Scientific Meetings and Published in Proceedings

B1. M. Gul, H. Uyarel, M. Ergelen, M. Ugur, C. Turkkan, E. Ayhan, T. Isık, O. Akgul, H. Unal Aksu, N. Uslu. Predictice value of neutrophil to lympocyte ratio in clinical outcomes of non-ST elevation myocardial infarction and unstable angina pectoris: 3-years follow-up. ESC Congress. 25-29 Agust 2012, Munich. Poster-872


C2. Chapters in National / International Books

1. İ.Bakır, E.Ödemiş, A.Yıldırım, H.Aksu, M.Gül, M.Paç, A.Akçevin, S.Aykut Aka, S.Büket, T.Sarıoğlu, Heart and Vascular Surgery (Transcatheter Valve Interventions), 1271-91 pp., Ankara, MN Medikal and Nobel Tıp Kitapevi, 2013


D. Articles Published in National Refereed Journals

D1. H.Aksu, S.Yılmazer, H.Hasdemir, HU.Aksu, T.Norgaz, Z.Nurkalem, S.Şahin, GF.Hobikoğlu, M.Ergelen. The relationship between severity and prevalence of coronary artery disease and carotid artery intima-media thickness and brachial artery endothelial function. Journal of Istanbul University Institute of Cardiology , 5-12 pp., 2010.

D2. O.Özer, T.Norgaz, M.Ertürk, H.Aksu, S.Yazıcı, H.Aksu, G.Hobikoğlu, E.Öntürk, E. Özal, A.Narin. The applicability of the Rose angina questionnaire in the Turkish population and its comparison with the results of exercise testing. Journal of MN-Cardiology , 25-29 pp., 2009

D3. Z.Nurkalem, AT.Alper, AL.Orhan, AE.Zencirci, I.Sari, B.Erer, HU.Aksu, DS.Ergün, HY.Yilmaz, M.Eren. Mean platelet volume in patients with slow coronary flow and its relationship with clinical presentation. Archives of the Turkish Society of Cardiology , 363-367 pp., 2008

D4.. AL.Orhan, Z.Nurkalem, H.Aksu, N.Sayar, M.Özdamar, B.Erer, H.Aksu, D.Ergün, F.Çiloğlu, H.Uyarel, M.Eren. The role of angiotensin converting enzyme gene insertion/deletion polymorphism in coronary slow flows. Journal of Istanbul University Institute of Cardiology , 10-14 pp., 2007

D5. Ş.Unal Dayı, N.Sayar, S.Terzi, N.Çakmak, Z.Tartan, H.Kaşıkçıoğlu, H.Uyarel, H.Ünal, Ö.Sürgit, N.Çam. The Effect of Body Mass Index on Mean Platelet Volume. MN-Cardiology , 25-29 pp., 2005

D6. Hale Ünal Aksu, Hüseyin Aksu, Ender Öner, Nilgün Işıksaçan, Ömer Çelik, Mehmet Ertürk, Ali Kemal Kalkan, Muhammed Hulusi Satılmışoğlu. Clopidogrel responsiveness in chronic kidney disease patients with acute coronary syndrome. March 2014, Dicle Medical Journal / Dicle Tip Dergisi 41(1):34-40

D7. Ender ÖNER, Şevket GÖRGÜLÜ, Hale AKSU, Ömer BAYCAN, Mehmet ERTÜRK , Ömer ÇELİK, Hulusi SATILMIŞOĞLU, Hüseyin AKSU. GRACE and TIMI scores in predicting the extension of coronary artery disease in patients with non-ST elevation myocardial infarction. Year 2015, Vol. 42 Issue: 2, 170 - 174, 08.07.2015


E. Papers Presented at National Scientific Meetings and Published in Proceedings

E1. M.Erturk, H.Unal Aksu, Ö.Çelik, M.Gül, F.Uzun, İ.F.Akturk, A.A.Yalcın, A.K.Kalkan, O.Surgit, M.K.Erol. Evaluation of the effect of mitral stenosis severity on left ventricular systolic function by isovolumic myocardial acceleration. 28th Turkish Cardiology Congress, , Antalya, Turkey, October 2012. Archives of the Turkish Society of Cardiology, October 2012, suplement 2, 51 pp.

E2. M.Gül, H.Uyarel, N.Uslu, A.Yıldırım, A.Eksik, M.K.Erol, Ö.Akgül, H.Ünal Aksu, E.Özal, H.Püşüroğlu, H.Aksu, İ.Bakır. Hematologic and clinical parameters after transcatheter aortic valve implantation in patients with advanced aortic stenosis. 28th Turkish Cardiology Congress, , Antalya, Turkey, October 2012. Archives of the Turkish Society of Cardiology, October 2012, suplement 2, 48 pp.

E3. M.Gül, A.Yıldırım, N.Uslu, A.Eksik, M.K.Erol, H.Uyarel, M.Ertürk, Ö.Sürgit, K.Erkanlı, Ü.Aydın, H.Ünal Aksu, Ö.Akgül, İ.Bakır. Results of transcatheter aortic valve implantation with Edwards SAPIEN and CoreValve devices: A single-center experience from Turkey. 28th Turkish Cardiology Congress, , Antalya, Turkey, October 2012. Archives of the Turkish Society of Cardiology, October 2012, suplement 2, 50 pp.

E4. M.Gul, M.Erturk, H.Unal Aksu ,A.K.Kalkan ,K.Oz ,O.Celik, A.Yildirim ,N.Uslu , M.K.Erol , I.Bakir. Rupture of the NovaFlex balloon during TAVI procedure and subsequent dissection of the right iliac arteries with ruptured balloon. 28th Turkish Cardiology Congress, , Antalya, Turkey, October 2012. Archives of the Turkish Society of Cardiology, October 2012, suplement 2, 325 pp.

E5. M.Erturk, M.Gul, H.Pushuroglu, H.Unal Aksu, M.Aslan, I.F.Akturk, O.Surgit, A.A.Yalcın, F.Uzun, M.K.Erol. Evaluation of atrial electromechanical sure and left atrial mechanical function in patients with secundum atrial septal defect. 27.

National Cardiology Congress. Istanbul, Turkey, October 2011. Archives of the Turkish Society of Cardiology, October 2011, suplement 1, 62 pp.

E6. I.F.Akturk , A.A.Yalcin , M.Erturk , F.Uzun , M.Gul , H.Unal Aksu , O.Surgit , S.Tugba. A rare complication of constrictive pericarditis: Large right ventricular aneurysm. 27th National Cardiology Congress. Istanbul, Turkey, October 2011. Archives of the Turkish Society of Cardiology, October 2011, suplement 1, 216 pp.

E7. M.Gul , O.Akgul , M.Erturk , H.Unal Aksu , A.A.Yalcın , O.Celik , K.Erkanli. Transcatheter aortic valve implantation through aortoiliac graft in a patient with bilateral aortoiliac grafts. 27th National Cardiology Congress. Istanbul, Turkey, October 2011. Archives of the Turkish Society of Cardiology, October 2011, suplement 1, 309 pp.

E8. N.Çakmak , E.Oguz, A.Akyol, A.Eksik , N.Sayar, M.Çakmak , H.Yılmaz , H.Hasdemir , İ.Erdinler, H.Ünal , K.Gürkan,. Comparison of Doppler echocardiographic features before and after ablation in patients with Wolf-Parkinson-White disease. XXI National Cardiology Congress. Antalya, Turkey, November 2005. Archives of the Turkish Society of Cardiology, October 2005, suplement 1, 21 pp.

E9. H.Aksu ,G.F.Hobikoğlu , T.Norgaz , O.Özer , M.Ertürk , A.Genç , H.Ünal , A.Narin. Are leukocyte subtypes associated with prognosis after acute coronary syndrome? XXI National Cardiology Congress. Antalya, Turkey, November 2005. Archives of the Turkish Society of Cardiology, October 2005, suplement 1, 81 pp.

E10. H.Aksu , G.F.Hobikoğlu , T.Norgaz , O.Özer , M.Ertürk , Z.Nurkalem ,H.Ünal , A.Genç , A.Narin. Relationship of mean platelet volume with prognosis after acute coronary syndrome. XXI National Cardiology Congress. Antalya, Turkey, November 2005. Archives of the Turkish Society of Cardiology, October 2005, suplement 1, 130 pp.

E11. S.U.Dayı, N.Sayar, N.Çakmak, H.Kaşıkçıoğlu, Z.Tartan, İ. Erdem, H.Unal, S.Terzi, N.Çam. The Effect of Body Mass Index on Mean Platelet Volume. XXth National Cardiology Congress. 511 pp, Antalya, Turkey, November 2004. Archives of the Turkish Society of Cardiology, October 2004, 511 pp.

E12. H.Ünal Aksu, N.Uslu, H.Aksu, O.F.Baycan, M.Erturk, A.Eksik. The short-term outcomes of mitraclip implantation: Single-center experience in Turkey. 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C44 pp.

E13. H.Unal Aksu, E.Oner, M.Erturk, H.Aksu, M. K.Erol. Aspirin resistance in patients with impaired renal function. 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C60 pp.

E14. H.Unal Aksu, Ş.Gorgulu, E.Oner, M.Erturk, O.Celik, H.Aksu. Feasibility of GRACE and TIMI Scores in Predicting the Extension of Coronary Artery Disease in Patients with Non ST Elevation Myocardial Infarction. . 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C212 pp.

E.15. M.Ertürk, A.Buturak, H.Pusuroğlu, A.K.Kalkan, M.Gürdogan, F.Uzun, O.Akgül, H.Ünal Aksu, F.Aktürk, N.Uslu. Evaluation of subclinical left and right ventricular dysfunction in dipper and non-dipper hypertensive patients using isovolumic acceleration. . 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C174 pp.

E16. M.Ertürk, E.Öner, A.K.Kalkan, H.Püsüroğlu, S.Özyılmaz, Ö.Akgül, H.Ünal Aksu, İ.F.Aktürk, Ö.Çelik, N.Uslu. The role of myocardial acceleration during isovolumic contraction in predicting subclinical right and left ventricular dysfunction in metabolic syndrome. . 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C173 pp.

E17. Ö.Çelik, M.M.Atasoy, M.Ertük, H.Ünal Aksu, A.A.Yalçın, I.F.Aktürk, M.Diker, I.Atasoy. Single dose ivabradine versus metoprolol for heart rate reduction before coronary computed tomography: In patients receiving calcium channel blocker therapy. . 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C85 pp.

E18. Ö.Çelik, A.Aydın, A.A.Yalçın, M.Ertürk, H.Ünal Aksu, I.F.Aktürk, H.Püşüroğlu, A.Birand. Morphologic and functional characteristics of LAD myocardial bridging on 64-detector MSCT coronary angiography: Correlation with coronary artery disease. . 29th Turkish Cardiology Congress. Antalya, Turkey, October 2013. JACC, October, 2013. Supplement C, C86 pp.


F. Other Publications

F1. M.K.Erol, H.Unal Aksu, N.Uslu, A.Eksik, H.Aksu, İ.Bakır, A.Yıldırım. Mitraclip in a patient with previous history of percutaneous coronary intervention (PCI). MitraClip Case Collection 2013.


Memberships

Turkish Society of Cardiology (TKD)

Turkish Medical Association (TTB)

European Society of Cardiology (ESC)

Medical Second Opinion
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