In Vitro Fertilization (IVF) Treatment

What is PRP?

In the PRP method, the blood taken from the patient is separated by a unique process, and plasma is obtained. The obtained plasma is rich in platelets, whose primary function is blood coagulation. This plasma is given back to the patient by injection. Platelets help cell regeneration with the growth factors they contain. Thanks to the PRP process, natural rejuvenation is achieved without giving foreign substances and drugs to the body with 3-4 applications at 2-4 weeks intervals.

PRP Method in IVF Treatment

IVF treatment gives couples the chance to have a baby naturally and with various assisted reproductive therapies. Especially in women, problems such as ovulation disorders and infertility can be seen in advanced age. If the desired success rate is not achieved despite the attempts for pregnancy, some support applications may be needed. The PRP method, used for tissue and organ regeneration in different branches, has been used for problems such as infertility, ovarian rejuvenation, and the removal of intrauterine membrane problems in the IVF process in recent years. With PRP application in the IVF treatment process is basically the process of returning the platelet-rich blood obtained from the patient's blood to the patient's uterus. In addition to bringing the uterine lining to the appropriate thickness, it can also improve poor ovarian reserve and increase egg quality.

PRP application in the IVF treatment process can basically be defined as the process of returning the platelet-rich blood obtained from the patient's own blood to the patient's uterus. In addition to bringing the uterine lining to the appropriate thickness, it can also be used to improve poor ovarian reserve and increase egg quality.

To Whom Can the PRP Method Be Applied in In Vitro Fertilization (IVF) Treatment?

One of the most critical parameters that increase the chance of conception in IVF treatment is the number of eggs and egg quality of the woman. One of the most essential factors affecting egg reserve is age. When the woman is over 37, the number of eggs decreases rapidly. Some women under the age of 40 may also have a rapid decrease in the number of eggs due to early menopause. Pregnancy can be achieved with in vitro fertilization treatment in women with reduced egg count. With the application of PRP to the ovaries in women with a history of early menopause in women with reduced egg numbers and women with poor egg and embryo quality, the chance of pregnancy can be increased by providing positive effects on the number and quality of eggs.

The uterine lining is another area where the PRP method is used in IVF. In case of damage to the endometrium (it may be damaged due to injections, recurrent curettage procedures, or intrauterine surgeries), this layer does not thicken, and a condition called thin endometrium occurs. Patients cannot become pregnant since the thin endometrium prevents the embryo from adhering to in vitro fertilization. In these patients with recurrent IVF failure, the adhesion (synechia) can be opened with hysteroscopy, and endometrial thickening can be achieved with repetitive endometrial PRP applications. Pregnancy is possible.

  • If we say that the PRP method can be applied to whom,
  • In women who have problems such as Wall of womb thickness and egg quality,
  • In those who fail in one or more IVF treatment attempts,
  • In women with reduced ovarian reserve,
  • It can be applied to women who are undergoing IVF treatment at an advanced age.

How is the PRP Method Applied in IVF Treatments?


PRP injection is made by entering the ovaries with an open needle, just like the egg collection process. Positive effects can be achieved on the number and quality of eggs.


It is the PRP procedure performed in the uterus. It can increase endometrial thickening in patients with thin endometrium in which the endometrium (the inner layer of the uterus) does not thicken and facilitate the attachment of the embryo, and increase the chance of pregnancy in women with recurrent IVF failure.

What are the Examination and Workup in the PRP Method?

Before the PRP application, an ultrasound examination and tests are performed to observe the woman's ovarian reserve, intrauterine findings, and uterus thickness. After these examinations and tests, the PRP method can be planned if a suitable candidate is found.

How to Follow Up After PRP Application?

Women who experience menstrual irregularity after the application may be recommended to use menstrual-regulating drugs.

After the application, control is carried out in the second or first menstrual period, depending on the follow-up and the physician's decision. During this examination, the ovaries and follicles are examined.

Created at 11.10.2023 06:20
Updated at 21.05.2024 10:40
Medical Second Opinion
✓ Valid

I have read the information from the General Data Protection Regulation. I accept that my data is processed within the specified scope and that I can be contacted by Medicana Health Group and Medicana Group Companies for health services and personal communication.

Medicana Hospital Business Inc. and Medicana Samsun Private Healthcare Services Inc.'s controlling and affiliated companies ("Medicana Health Group") can provide all kinds of information, questionnaires, publicity, opening, invitations. and activity etc. I agree to send Commercial Electronic Messages (call, sms, e-mail, etc.) to me within the scope of reminders and other communication activities.


Let Us Call You